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RAD18 Mouse anti-Human, Clone:2G8D12, Abnova™

Catalog No. 89333493 Shop All Abnova Corporation Products
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89-333-493 100 μg
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Catalog No. 89-333-493 Supplier Abnova Corporation Supplier No. MAB17130
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Description

Mouse monoclonal antibody raised against recombinant human RAD18.

The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq]

Specifications

Antigen RAD18
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 2G8D12
Conjugate Unconjugated
Description RAD18 homolog (S. cerevisiae)
Dilution ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry
Immunocytochemistry
Flow Cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.
Formulation In PBS (0.05% sodium azide)
Gene RAD18
Gene Alias RNF73
Host Species Mouse
Immunogen Recombinant protein corresponding to amino acid 332-430 of human RAD18 from E. coli.
Quantity 100 μg
Gene ID (Entrez) 56852
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Liquid
Isotype IgG1
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