Invitrogen™ RAD21 Monoclonal Antibody (CM110-2C10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA116585

Catalog No. AMPA6585

Description

In Western blot, two bands are seen: the full-length Rad21 is seen around 130 kDa, while the cleaved Rad21 is seen around 70 kDa. Suggested positive control: antigen standard for RAD21 (transient overexpression lysate), Hela whole cell extract.

This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.

Specifications

• Antigen: RAD21
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: O60216, Q61550
• Gene Symbols: Rad21
• Immunogen: N-terminus fusion protein of the C-terminal fragment (residues 544-631) of the Scc1 subunit of human cohesin.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Western Blot
• Clone: CM110-2C10
• Conjugate: Unconjugated
• Gene: Rad21
• Gene Alias: 64-kDa carboxy-terminal product; 64-kDa C-terminal product; 65-kDa carboxy-terminal product; CDLS4; double-strand-break repair protein rad21 homolog; double-strand-break repair protein rad21-like protein; FLJ25655; FLJ40596; h NXP-1; hHR21; HR21; HRAD21; KIAA0078; KIAA0078RAD21; kleisin; MCD1; mHR21; mKIAA0078; nuclear matrix protein 1; NXP1; NXP-1; Pokeweed agglutinin-binding protein 29; protein involved in DNA double-strand break repair; PW29; Rad21; RAD21 cohesin complex component; RAD21 homolog; RAD21 homolog (S. pombe); SCC1; SCC1 homolog; sister chromatid cohesion 1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 19357, 5885
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid