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Rad21 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501556856
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50-155-6856 20 μL
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Catalog No. 50-155-6856 Supplier Bethyl Laboratories, Inc Supplier No. A300080AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Bovine

The cohesin complex plays an important role in tethering sister chromatids during the prophase through anaphase stages of mitosis, making certain that genomic information is replicated accurately. As the cellular division process continues, separase destroys the cohesin complex by means of cleavaging its Scc1 subunit, allowing the chromatids to separate and divide with the cell. During apoptosis the C-terminal portion of hRad21 is cleaved and translocated to the cytoplasm. This cleavage and translocation may act as a nuclear signal that promotes and accelerates subsequent events of apoptosis.

Specifications

Antigen Rad21
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene RAD21
Gene Accession No. O60216, Q61550
Gene Alias double-strand-break repair protein rad21 homolog, hHR21, HR21, KIAA0078RAD21, MCD1, Nuclear matrix protein 1, NXP-1, HRAD21, protein involved in DNA double-strand break repair, SCC1 homolog
Gene Symbols Rad21
Host Species Rabbit
Immunogen Between 575 and C-term
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19357, 5885
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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