RAD23B Mouse anti-Human, Clone: OTI7C5, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF804866

Catalog No. 50-166-7181

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

Specifications

• Antigen: RAD23B
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: RAD23B
• Gene Alias: HHR23B, HR23B, P58
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5887
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI7C5
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P54727
• Gene Symbols: RAD23B
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-253 of human RAD23B produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1