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RAD23B Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501572496
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50-157-2496 10 μL
50-157-2495 100 μL
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Catalog No. 50-157-2496 Supplier Bethyl Laboratories, Inc Supplier No. IHC00663T
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Chicken, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Pig, Panda, Orangutan,

The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

Specifications

Antigen RAD23B
Applications Immunofluorescence, Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene RAD23B
Gene Accession No. P54727
Gene Alias HHR23B, HR23B, P58, RAD23, yeast homolog of, B, UV excision repair protein RAD23 homolog B, XP-C repair complementing complex 58 kDa, XP-C repair complementing protein, XP-C repair-complementing complex 58 kDa protein
Gene Symbols RAD23B
Host Species Rabbit
Immunogen Between 359 and 409
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5887
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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