RAD50 Mouse anti-Human, Rat, Clone:3D2G10, Abnova™

Catalog No.	Quantity
89-333-580	100 μg

Catalog No. 89-333-580 Supplier Abnova Corporation Supplier No. MAB17199

Description

Mouse monoclonal antibody raised against recombinant human RAD50.

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq]

Specifications

• Antigen: RAD50
• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 3D2G10
• Conjugate: Unconjugated
• Description: RAD50 homolog (S. cerevisiae)
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunohistochemistry (1:200-1:1000)
  Immunocytochemistry
  Flow Cytometry (1:200-1:400)
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: RAD50
• Gene Alias: RAD50-2, hRad50
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acid 228-359 of human RAD50 from E. coli.
• Quantity: 100 μg
• Gene ID (Entrez): 10111
• Target Species: Human, Rat
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a