Invitrogen™ RAD50 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531554

Catalog No. PIPA531554

Description

Recommended positive controls: HeLa, NT2D1, Neuro2A, GL261, PC-12. Predicted reactivity: Mouse (92%), Rat (91%), Rabbit (92%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Rad50-13B3 recognizes human Rad50, a 153a protein involved in DNA double strand break repair. Rad50 is associated with Mre11 and p95 (Nibrin) to form a multiprotein complex involved in the double strand break repair process. Upon DNA damage, Rad50 and Mre11 redistribute and are co-localized within the nucleus of damaged cells.

Specifications

• Antigen: RAD50
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAD50
• Gene Alias: 153 kDa protein; DNA repair protein RAD50; hRad50; hsRAD50; I79_004319; mRad50; Mrell; MRX complex DNA-binding subunit; N0872; NBSLD; Rad50; RAD50 2; RAD50 double strand break repair protein; RAD50 homolog (S. cerevisiae); RAD50 homolog, double strand break repair protein; RAD50 PEN; RAD502; RAD50-2; RAD50-3; Rad50l; YNL250W
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10111, 19360, 64012
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.78 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P70388, Q92878, Q9JIL8
• Gene Symbols: RAD50
• Immunogen: Recombinant fragment corresponding to a region within amino acids 128 and 420 of Human Rad50.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG