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RAD51C Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501563110
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50-156-3110 100 μL
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Catalog No. 50-156-3110 Supplier Bethyl Laboratories, Inc Supplier No. A302645A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.

Specifications

Antigen RAD51C
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene RAD51C
Gene Accession No. O43502
Gene Alias DNA repair protein RAD51 homolog 3, RAD51 homolog C (S. cerevisiae), RAD51L2, Yeast RAD51 homolog 3
Gene Symbols RAD51C
Host Species Rabbit
Immunogen Between 326 and 376
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5889
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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