RAD51L1 Mouse anti-Human, Clone: OTI7H4, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF503550

Catalog No. 50-166-2212

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.

Specifications

• Antigen: RAD51L1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: RAD51B
• Gene Alias: R51H2, RAD51L1, REC2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5890
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI7H4
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: O15315
• Gene Symbols: RAD51B
• Immunogen: Human recombit protein fragment corresponding to amino acids 119-346 of human RAD51L1 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1