Invitrogen™ RAD52 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565036

Catalog No. PIPA565036

Description

Immunogen sequence: ILGGRDSHPAA GGGSVLCFGQ CQYTAEEYQA IQKALRQRLG PEYISSRMAG GGQKVCYIEG HRVINLANEM FGYNGWAHSI TQQNVDFVDL NNGKFYVGVC AFVRVQLKDG SYHEDVGYGV SE Highest antigen sequence identity to the following orthologs - mouse 90%, rat 90%.

DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions. Double-strand breaks are generally thought to be repaired via one of two distinct mechanisms: homologous recombination (HR) or non-homologous end joining (NHEJ). Homologous recombination requires the activity of the members of the RAD52 epistasis group, which includeRAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2. RAD52 can catalyze strand annealing reactions, and can form oligomers that attach to ends of single-stranded DNA.

Specifications

• Antigen: RAD52
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAD52
• Gene Alias: DNA repair protein RAD52 homolog; RAD52; RAD52 homolog (S. cerevisiae); RAD52 homolog, DNA repair protein; Rad52yh; recombination protein RAD52; rhabdomyosarcoma antigen MU-RMS-40.23
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5893
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P43351
• Gene Symbols: RAD52
• Immunogen: Recombinant Human RAD52. Recombinant protein control fragment (Product #RP-105801).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG