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Invitrogen™ RAD54L2 Polyclonal Antibody
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Catalog No. PIPA589311
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100 μL
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PIPA589311 100 μL
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Catalog No. PIPA589311 Supplier Invitrogen™ Supplier No. PA589311
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ELQQYADVAA ARESRQSSPS TNAALPGPPA QLMDSSAVPG TALGTEPRLG GHCLNSSLLV TGQPCGDRHP VLDLRGHKRK LATPPAAQES SRRRSRKGHL PAPVQPYEHG YPVSGGFAMP PVSLNHNLTT PFTSQAGENS LFMGSTPSYY QLSNLLADAR LVFPVTTDPL VPAGPVSSSS TATSVTASNP SFMLNPSVPG ILPSYSLPFS QPLLSEPRMF APFPSPVLPS NLSRGMSIYP GYMSPHAGYP AGGLLRSQVP PFDSHEVAEV GFSSNDDEDK DDDVIEVTGK.

Adrenergic receptors (ARs) include four general types (a1, a2, b1 and b2) that are found in different target tissues and differ in their affinities and responses to various agonists and antagonists. The coupling of ARs to specific intracellular effectors is mediated through diverse heterotrimeric G proteins. ARs play a critical role in the development of prostate cancer, and transcriptional activity of AR is partly regulated by coregulatory proteins. RAD54L2 (RAD54-like 2), also known as ARIP4 (androgen receptor-interacting protein 4), HSPC325 or SRISNF2L, is a 1,467 amino acid nuclear protein belonging to the SNF2/RAD54 helicase family that consists of one helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 is a DNA helicase that regulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. RAD54L2 is post-translationally sumoylated or phosphorylated upon DNA damage.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAD54L2
Applications ELISA, Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RAD54L2
Gene Accession No. Q9Y4B4
Gene Alias Androgen receptor-interacting protein 4; AR interacting protein 4; ARIP4; Helicase ARIP4; HSPC325; KIAA0809; Rad54 like 2; RAD54L2; RAD54-like 2 (S. cerevisiae); RAD54-like protein 2; RGD1561889; SRISNF2L
Gene Symbols RAD54L2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1178-1467 of human RAD54L2 (NP_0559212).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23132
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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