Invitrogen™ RAD54L2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589311

Catalog No. PIPA589311

Description

Immunogen sequence: ELQQYADVAA ARESRQSSPS TNAALPGPPA QLMDSSAVPG TALGTEPRLG GHCLNSSLLV TGQPCGDRHP VLDLRGHKRK LATPPAAQES SRRRSRKGHL PAPVQPYEHG YPVSGGFAMP PVSLNHNLTT PFTSQAGENS LFMGSTPSYY QLSNLLADAR LVFPVTTDPL VPAGPVSSSS TATSVTASNP SFMLNPSVPG ILPSYSLPFS QPLLSEPRMF APFPSPVLPS NLSRGMSIYP GYMSPHAGYP AGGLLRSQVP PFDSHEVAEV GFSSNDDEDK DDDVIEVTGK.

Adrenergic receptors (ARs) include four general types (a1, a2, b1 and b2) that are found in different target tissues and differ in their affinities and responses to various agonists and antagonists. The coupling of ARs to specific intracellular effectors is mediated through diverse heterotrimeric G proteins. ARs play a critical role in the development of prostate cancer, and transcriptional activity of AR is partly regulated by coregulatory proteins. RAD54L2 (RAD54-like 2), also known as ARIP4 (androgen receptor-interacting protein 4), HSPC325 or SRISNF2L, is a 1,467 amino acid nuclear protein belonging to the SNF2/RAD54 helicase family that consists of one helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 is a DNA helicase that regulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. RAD54L2 is post-translationally sumoylated or phosphorylated upon DNA damage.

Specifications

• Antigen: RAD54L2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAD54L2
• Gene Alias: Androgen receptor-interacting protein 4; AR interacting protein 4; ARIP4; Helicase ARIP4; HSPC325; KIAA0809; Rad54 like 2; RAD54L2; RAD54-like 2 (S. cerevisiae); RAD54-like protein 2; RGD1561889; SRISNF2L
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23132
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9Y4B4
• Gene Symbols: RAD54L2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1178-1467 of human RAD54L2 (NP_0559212).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov