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Invitrogen™ RADIL Polyclonal Antibody
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Catalog No. PIPA523742
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400 μL
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PIPA523742 400 μL
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Catalog No. PIPA523742 Supplier Invitrogen™ Supplier No. PA523742
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Description

Rabbit Polyclonal Antibody

RADIL Polyclonal Antibody for Western Blot, IHC (P)

Radil is a broadly expressed adapter protein that contains a RA-like domain, a PDZ domain and a DIL domain. Like RAPL and RIAM, Radil interacts preferentially with active GTP-bound Rap1, and overexpression of Radil enhances integrin-mediated adhesion. In addition, Radil knock down inhibits cell-substrate adhesion in HT1080, AD293, and NMuMG cells and results in migration defects in SW1353 and zebrafish neural crest cells. Radil regulates neutrophil adhesion by specifically enhancing beta2-integrin activation, as well as focal adhesion kinase (FAK) and paxillin phosphorylation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RADIL
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene RADIL
Gene Accession No. Q96JH8
Gene Alias AI536456; D930005D10Rik; KIAA1849; Radil; Rap associating with DIL domain; Rap GTPase interactor; Ras association and DIL domains; ras-associating and dilute domain-containing protein; RASIP2
Gene Symbols RADIL
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 1044-1071 amino acids from the C-terminal region of human RADIL.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55698
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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