Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA562479

Invitrogen™ RADIL Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA562479
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA562479 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA562479 Supplier Invitrogen™ Supplier No. PA562479
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: YGTHFIMSPP TKSKLKRQSQ LLSSMLSRTL SYKYRDLDST FSSLGASDDP AELSTQLSAP GVLKVFGDSV CTGTHYKSVL A Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 95%.

Radil is a broadly expressed adapter protein that contains a RA-like domain, a PDZ domain and a DIL domain. Like RAPL and RIAM, Radil interacts preferentially with active GTP-bound Rap1, and overexpression of Radil enhances integrin-mediated adhesion. In addition, Radil knock down inhibits cell-substrate adhesion in HT1080, AD293, and NMuMG cells and results in migration defects in SW1353 and zebrafish neural crest cells. Radil regulates neutrophil adhesion by specifically enhancing beta2-integrin activation, as well as focal adhesion kinase (FAK) and paxillin phosphorylation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RADIL
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RADIL
Gene Accession No. Q96JH8
Gene Alias AI536456; D930005D10Rik; KIAA1849; Radil; Rap associating with DIL domain; Rap GTPase interactor; Ras association and DIL domains; ras-associating and dilute domain-containing protein; RASIP2
Gene Symbols RADIL
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RADIL. Recombinant protein control fragment (Product #RP-101382).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55698
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.