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Invitrogen™ RAE1 gamma Polyclonal Antibody
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Catalog No. PIPA547078
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100 μg
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PIPA547078 100 μg
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Catalog No. PIPA547078 Supplier Invitrogen™ Supplier No. PA547078
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Description

Goat Polyclonal Antibody

This antibody detects mouse Rae-1 gamma as well as mouse Rae-1 alpha, 1 beta, 1 gamma and 1 epsilon in direct ELISAs and Western blots. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAE1 gamma
Applications Immunohistochemistry (Frozen), Neutralization, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Raet1c
Gene Accession No. O08604
Gene Alias dJ481F12.3; dJ800J21.1; MIG14; Mnrp41; mRNA export factor; mRNA export protein; MRNP41; RAE-1gamma; RAE-1-gamma; Raet1c; retinoic acid early transcript gamma; retinoic acid early-inducible protein 1-gamma; RP4-800J21.2
Gene Symbols Raet1c
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse Rae-1 gamma Leu29-Ser231.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19370
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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