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Invitrogen™ RAE1 Polyclonal Antibody
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Catalog No. PIPA521739
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100 μL
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PIPA521739 100 μL
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Catalog No. PIPA521739 Supplier Invitrogen™ Supplier No. PA521739
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HeLaS3, Molt-4, Raji. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Chimpanzee (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAE1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 10% glycerol and 0.01% thimerosal; pH 7
Gene RAE1
Gene Accession No. P78406
Gene Alias 3230401I12Rik; 41; D2Ertd342e; dJ481F12.3; dJ800J21.1; FLJ30608; HGNC:9828; homolog of yeast Rae1 (Bharathi) mRNA-associated protein of 41 kDa (Kraemer); MGC117333; MGC126076; MGC126077; MIG14; migration-inducing gene 14; MNRP; Mnrp41; mRNA export factor; mRNA export factor-like protein; mRNA export protein; mRNA-associated protein MRNP 41; mRNA-binding protein, 41-kD; MRNP41; OTTHUMP00000166110; rae1; RAE1 (RNA export 1, S.pombe) homolog; rae1 protein; rae1 protein homolog; RAE1 RNA export 1 homolog; RAE1 RNA export 1 homolog (S. pombe); ribonucleic acid export 1; RP4-800J21.2; zgc:56449; zgc:77723
Gene Symbols RAE1
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RAE1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8480
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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