Invitrogen™ RAE1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA541739

Catalog No. PIPA541739

Description

Peptide sequence: SACCFNHNGN IFAYASSYDW SKGHEFYNPQ KKNYIFLRNA AEELKPRNKK Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: RAE1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAE1
• Gene Alias: 3230401I12Rik; 41; D2Ertd342e; dJ481F12.3; dJ800J21.1; FLJ30608; HGNC:9828; homolog of yeast Rae1 (Bharathi) mRNA-associated protein of 41 kDa (Kraemer); MGC117333; MGC126076; MGC126077; MIG14; migration-inducing gene 14; MNRP; Mnrp41; mRNA export factor; mRNA export factor-like protein; mRNA export protein; mRNA-associated protein MRNP 41; mRNA-binding protein, 41-kD; MRNP41; OTTHUMP00000166110; rae1; RAE1 (RNA export 1, S.pombe) homolog; rae1 protein; rae1 protein homolog; RAE1 RNA export 1 homolog; RAE1 RNA export 1 homolog (S. pombe); ribonucleic acid export 1; RP4-800J21.2; zgc:56449; zgc:77723
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8480
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P78406
• Gene Symbols: RAE1
• Immunogen: Synthetic peptide directed towards the C-terminal of human RAE1 (aa 319-368).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov