Invitrogen™ Rafivirumab Humanized Recombinant Human Monoclonal Antibody

Catalog No.	Quantity
PIMA541727	100 μg

Catalog No. PIMA541727 Supplier Invitrogen™ Supplier No. MA541727

Description

Human Recombinant Monoclonal Antibody

Endotoxin level < 0.01EU/μg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.

Rafivirumab is a biosimilar that targets the Rabies virus and is used for phrophylaxis. Rabies virus (Neurotropic lyssavirus) is a member of the Rhabdoviridae family. Rabies is a single stranded, neurotropic, negative sense RNA virus which encodes 5 proteins: a glycoprotein, a nucleoprotein, and three others. The mature virus has a bullet shape, a protein coat, and a lipid envelope. The outer surface of the virus is covered with thumblike glycoprotein projections 5-10 nm long and 3 nm in diameter. The virus averages approximately 780 nm in length. Virus infectivity is destroyed by lipid solvents. Rabies virus is a very successful virus, with a very wide range of hosts. It causes an acute, central nervous system infection, characterized by CNS irritation, followed by paralysis and death. Approximately 50,000 human deaths each year are caused by rabies.

Specifications

• Antigen: Rafivirumab Humanized
• Applications: ELISA, SDS-Page
• Classification: Recombinant Monoclonal
• Concentration: 4.06 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.4
• Gene Alias: CR57
• Host Species: Human
• Immunogen: Rabies virus RV.
• Purification Method: Protein A/G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Virus
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 λ
• Target Molecule: Chemical