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Invitrogen™ RALA Monoclonal Antibody (4G8B11)
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Catalog No. PIMA531890
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100 μL
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Catalog No. Quantity
PIMA531890 100 μL
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Catalog No. PIMA531890 Supplier Invitrogen™ Supplier No. MA531890
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Description

Mouse Monoclonal Antibody

MA5-31890 has been tested in indirect ELISA.

Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RALA
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 4G8B11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene Rala
Gene Accession No. P11233, P63321
Gene Alias 3010001O15Rik; AW322615; MGC48949; Ral; -ral simian leukemia viral oncogene homolog A (ras related); RALA; Ral-a; ral-A protein; RALA Ras like proto-oncogene A; Ras family small GTP binding protein RALA; ras related GTP binding protein A; Rasl1; RAS-like protein A; RAS-like, family 1; ras-related protein Ral-A; v-ral simian leukemia viral oncogene homolog A (ras related)
Gene Symbols Rala
Host Species Mouse
Immunogen Purified recombinant fragment of human RALA (AA: 71-203) expressed in E. coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56044, 5898
Target Species Human, Mouse, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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