Invitrogen™ RALA Monoclonal Antibody (4G8B11)

Catalog No.	Quantity
PIMA531890	100 μL

Catalog No. PIMA531890

Supplier: Invitrogen™ MA531890

Description

Mouse Monoclonal Antibody

MA5-31890 has been tested in indirect ELISA.

Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.

Specifications

• Antigen: RALA
• Applications: ELISA, Flow Cytometry, Western Blot
• Classification: Monoclonal
• Clone: 4G8B11
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% sodium azide
• Gene: Rala
• Gene Accession No.: P11233, P63321
• Gene Alias: 3010001O15Rik; AW322615; MGC48949; Ral; -ral simian leukemia viral oncogene homolog A (ras related); RALA; Ral-a; ral-A protein; RALA Ras like proto-oncogene A; Ras family small GTP binding protein RALA; ras related GTP binding protein A; Rasl1; RAS-like protein A; RAS-like, family 1; ras-related protein Ral-A; v-ral simian leukemia viral oncogene homolog A (ras related)
• Gene Symbols: Rala
• Host Species: Mouse
• Immunogen: Purified recombinant fragment of human RALA (AA: 71-203) expressed in E. coli.
• Purification Method: Protein G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 56044, 5898
• Target Species: Human, Mouse, Monkey
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1