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Invitrogen™ RALA Polyclonal Antibody
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Catalog No. PIPA5102958
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100 μL
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PIPA5102958 100 μL
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Catalog No. PIPA5102958 Supplier Invitrogen™ Supplier No. PA5102958
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RALA.

Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RALA
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Rala
Gene Accession No. P11233
Gene Alias 3010001O15Rik; AW322615; MGC48949; Ral; -ral simian leukemia viral oncogene homolog A (ras related); RALA; Ral-a; ral-A protein; RALA Ras like proto-oncogene A; Ras family small GTP binding protein RALA; ras related GTP binding protein A; Rasl1; RAS-like protein A; RAS-like, family 1; ras-related protein Ral-A; v-ral simian leukemia viral oncogene homolog A (ras related)
Gene Symbols Rala
Host Species Rabbit
Immunogen A synthesized peptide derived from human RALA(Accession P11233), corresponding to amino acid residues F168-L206.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5898
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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