Invitrogen™ RALBP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA543788

Catalog No. PIPA543788

Description

Peptide sequence: MTECFLPPTS SPSEHRRVEH GSGLTRTPSS EEISPTKFPG LYRTGEPSPP Sequence homology: Cow: 100%; Dog: 100%; Goat: 86%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%.

Can specifically activate hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

Specifications

• Antigen: RALBP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RALBP1
• Gene Alias: 76 kDa Ral-interacting protein; Cytocentrin; dinitrophenyl S-glutathione ATPase; DNP-SG ATPase; ralA binding protein 1; ralA-binding protein 1; RALBP1; Ral-interacting protein 1; RIP; RIP1; RLIP1; RLIP76
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10928
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q15311
• Gene Symbols: RALBP1
• Immunogen: Synthetic peptide directed towards the N-terminal of human RALBP1 (aa 1-50).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG