Invitrogen™ RALBP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579912

Catalog No. PIPA579912

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human placenta tissue, human HepG2 whole cell, human SGC-7901 whole cell, human 22RV1 whole cell, rat lung tissue, mouse lung tissue, mouse testis tissue, mouse ovary tissue. IHC: human ovary cancer tissue, human placenta tissue, mouse small intestine tissue, rat small intestine tissue. ICC/IF: U20S cell. Flow: U20S cell.

Can specifically activate hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

Specifications

• Antigen: RALBP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RALBP1
• Gene Alias: 76 kDa Ral-interacting protein; Cytocentrin; dinitrophenyl S-glutathione ATPase; DNP-SG ATPase; ralA binding protein 1; ralA-binding protein 1; RALBP1; Ral-interacting protein 1; RIP; RIP1; RLIP1; RLIP76
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10928, 19765, 84014
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: Q15311, Q62172, Q62796
• Gene Symbols: RALBP1
• Immunogen: E. coli-derived human RALBP1 recombinant protein (Position: K239-Q506).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov