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Invitrogen™ RALBP1 Polyclonal Antibody
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Catalog No. PIPA579912
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100 μg
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PIPA579912 100 μg
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Catalog No. PIPA579912 Supplier Invitrogen™ Supplier No. PA579912
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human placenta tissue, human HepG2 whole cell, human SGC-7901 whole cell, human 22RV1 whole cell, rat lung tissue, mouse lung tissue, mouse testis tissue, mouse ovary tissue. IHC: human ovary cancer tissue, human placenta tissue, mouse small intestine tissue, rat small intestine tissue. ICC/IF: U20S cell. Flow: U20S cell.

Can specifically activate hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RALBP1
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene RALBP1
Gene Accession No. Q15311, Q62172, Q62796
Gene Alias 76 kDa Ral-interacting protein; Cytocentrin; dinitrophenyl S-glutathione ATPase; DNP-SG ATPase; ralA binding protein 1; ralA-binding protein 1; RALBP1; Ral-interacting protein 1; RIP; RIP1; RLIP1; RLIP76
Gene Symbols RALBP1
Host Species Rabbit
Immunogen E. coli-derived human RALBP1 recombinant protein (Position: K239-Q506).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10928, 19765, 84014
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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