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Invitrogen™ RAMP1 Polyclonal Antibody
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Catalog No. PIPA518958
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100 μg
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PIPA518958 100 μg
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Catalog No. PIPA518958 Supplier Invitrogen™ Supplier No. PA518958
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Goat Polyclonal Antibody

This antibody is predicted to react with human and mouse based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAMP1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene RAMP1
Gene Accession No. Q9JJ74
Gene Alias 9130218E19Rik; calcitonin receptor-like receptor activity modifying protein 1; calcitonin-receptor-like receptor activity-modifying protein 1; CRLR activity-modifying protein 1; MGC38240; RAMP1; receptor (calcitonin) activity modifying protein 1; receptor (G protein-coupled) activity modifying protein 1; receptor activity modifying protein 1; receptor activity-modifying protein 1
Gene Symbols RAMP1
Host Species Goat
Immunogen Synthetic peptide sequence (DYQSKRTEGIV) corresponding to the C-terminus amino acids of Ramp1 (aa 144-148).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 58965
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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