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Invitrogen™ RAMP2 Polyclonal Antibody
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Catalog No. PIPA565695
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100 μL
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PIPA565695 100 μL
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Catalog No. PIPA565695 Supplier Invitrogen™ Supplier No. PA565695
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PLPTTGTPGSE GGTVKNYETA VQFCWNHYKD QMDPIEKDWC DWAMISRPYS TLRDCLEHFA ELFDLGFPNP LAERIIFETH QIHFANCSLV QP Highest antigen sequence identity to the following orthologs - mouse 55%, rat 56%.

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAMP2
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Ramp2
Gene Accession No. O60895
Gene Alias calcitonin receptor-like receptor activity modifying protein 2; calcitonin-receptor-like receptor activity-modifying protein 2; CRLR activity-modifying protein 2; OTTMUSP00000002615; OTTMUSP00000037624; Ramp2; receptor (calcitonin) activity modifying protein 2; receptor (G protein-coupled) activity modifying protein 2; receptor activity modifying protein 2; receptor activity modifying protein 2 isoform; receptor activity-modifying protein 2; receptor-activity-modifying protein 2; RP23-281C18.6
Gene Symbols Ramp2
Host Species Rabbit
Immunogen Recombinant Human RAMP2. Recombinant protein control fragment (Product #RP-106369).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10266
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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