RANBP1 Mouse anti-Human, Clone: OTI8E1, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF811554

Catalog No. 50-167-0718

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.

Specifications

• Antigen: RANBP1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: RANBP1
• Gene Alias: HTF9A
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5902
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI8E1
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P43487
• Gene Symbols: RANBP1
• Immunogen: Full length human recombit protein of human RANBP1 produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b