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Invitrogen™ RANBP1 Polyclonal Antibody
Goat Polyclonal Antibody
Supplier: Invitrogen™ PA19093
Description
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
Specifications
RANBP1 | |
Polyclonal | |
Unconjugated | |
RANBP1 | |
HpaII tiny fragments locus 9A; hpaII tiny fragments locus 9a protein; Htf9a; Htf9-a; Htf9-a/RanBP1; RAN binding protein 1; ran-binding protein 1; RANBP1; RANG; Ran-specific GTPase-activating protein; testis secretory sperm-binding protein Li 221n | |
Goat | |
Ammonium sulfate precipitation | |
RUO | |
5902 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
0.5 mg/mL | |
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
P43487 | |
RANBP1 | |
Synthetic peptide corresponding to the C terminus amino acids LSVKEETKEDAEEKQ (aa 187-201). | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |
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