Invitrogen™ RANBP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5141086

Catalog No. PIPA5141086

Description

RANBP1 Polyclonal Antibody for Western Blot, IHC (P)

Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.

Specifications

• Antigen: RANBP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RANBP1
• Gene Alias: HpaII tiny fragments locus 9A; hpaII tiny fragments locus 9a protein; Htf9a; Htf9-a; Htf9-a/RanBP1; RAN binding protein 1; ran-binding protein 1; RANBP1; RANG; Ran-specific GTPase-activating protein; testis secretory sperm-binding protein Li 221n
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19385, 360739, 5902
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P34022, P43487
• Gene Symbols: RANBP1
• Immunogen: Synthetic peptide within N-terminal human RanBP1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG