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RanBP1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501735763 Shop All Proteintech Group Inc Products
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50-173-5763 150 μL
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Catalog No. 50-173-5763 Supplier Proteintech Group Inc Supplier No. 278041AP150UL
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Rabbit Polyclonal Antibody

Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.

Specifications

Antigen RanBP1
Applications Western Blot
Classification Polyclonal
Concentration 0.53 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene RANBP1
Gene Accession No. P34022, P43487
Gene Alias HTF9A, RAN binding protein 1, RANBP1
Gene Symbols RANBP1
Host Species Rabbit
Immunogen RanBP1 Fusion Protein Ag25714
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19385, 5902
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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