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RanBP1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988986
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100 μL
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50-198-8986 100 μL
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Catalog No. 50-198-8986 Supplier Bioss Supplier No. BS9322R
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Description

Rabbit Polyclonal Antibody

Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.

Specifications

Antigen RanBP1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene RANBP1
Gene Accession No. P43487
Gene Alias HpaII tiny fragments locus 9A; HpaII tiny fragments locus 9a protein; Htf9a; Htf9-a; Htf9-a/RanBP1; RAN binding protein 1; Ran-binding protein 1; Ranbp1; RANG; Ran-specific GTPase-activating protein; testis secretory sperm-binding protein Li 221n
Gene Symbols RANBP1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human RanBP1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5902
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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