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Invitrogen™ RANBP10 Polyclonal Antibody
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Catalog No. PIPA5117680
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100 μg
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Catalog No. Quantity
PIPA5117680 100 μg
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Catalog No. PIPA5117680 Supplier Invitrogen™ Supplier No. PA5117680
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Description

Rabbit Polyclonal Antibody

This antibody has been tested in direct-ELISA.

The RAN binding protein 10 (RANBP10) is a cytoplasmic guanine nucleotide exchange factor that shares high sequence similarity to the MET-interacting protein RANBP9. RANBP10 is expressed in the cytoplasm of mature megakaryocytes (MKs) and platelets where it localizes to polymerized noncentrosomal microtubules. RANBP10 possesses guanine nucleotide exchange factor activity towards RAN, a GTPase involved in nucleocytoplasmic traffic, spindle formation at mitosis, and nuclear envelope assembly during telophase, suggesting that RANBP10 may also be involved in these activities. RANBP10 depletion in vitro caused the disturbance of polymerized filaments in MKs and platelets in RANBP10-null mice exhibited disorders in microtubule filament numbers and localization, indicating that RANBP10 may play a significant role in maintaining microtubule dynamics.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RANBP10
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 2.11 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene RANBP10
Gene Accession No. Q6VN20
Gene Alias 4432417N03Rik; KIAA1464; RAN binding protein 10; ran-binding protein 10; RANBP10; rangef; RGD1311587
Gene Symbols RANBP10
Host Species Rabbit
Immunogen Recombinant Human Ran-binding protein 10 protein (3-165aa).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 361396, 57610
Target Species Human, Rat
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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