Invitrogen™ RANBP3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA1084

Catalog No. PA1084

Description

PA1-084 detects Ran binding protein 3 (RanBP3) from human and rat cells. PA1-084 has been successfully used in Western blot and immunofluorescence procedures. By Western blot this antibody detects an ~60 kDa protein representing RanBP3 from HeLa cell extracts. Immunofluorescence staining of RanBP3 in NRK cells with PA1-084 results in diffuse nuclear staining. The PA1-084 immunogen is a synthetic peptide corresponding to residues M(1) A D L A N E E K P A L A(13) C of human RanBP3. The PA1-084 immunizing peptide (Cat. # PEP-177) is available for use in neutralization and control experiments.

Ran binding protein 3 (RanBP3) is a member of Ran GTPase binding proteins that is located at the nuclear pore complex (NPC) and plays an essential role in the transport between cytoplasm and nucleus. RANPB3 is expessed as two spliced forms, RanBP3a and RanBP3b, both of which contains two FXFG motifs, characteristic of a subgroup of nucleoporins in addition to nuclear localization signal in the amino-terminal region (amino acid residues 40-57) and a unique acidic carboxyl terminus which is integral to its switch function.

Specifications

• Antigen: RANBP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RANBP3
• Gene Alias: 2610024N24Rik; AA408221; RAN binding protein 3; RANB3; ran-binding protein 3; RAN-binding protein-3; Ranbp3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 501281, 8498
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1 mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: Q9H6Z4
• Gene Symbols: RANBP3
• Immunogen: Synthetic peptide corresponding to residues M(1) A D L A N E E K P A L A(13) C of human RanBP3.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG