RanBP7 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-8666	100 μL

Catalog No. 50-198-8666 Supplier Bioss Supplier No. BS8590R

Description

Rabbit Polyclonal Antibody

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of RaNULLs GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.

Specifications

• Antigen: RanBP7
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: Ipo7
• Gene Accession No.: O95373
• Gene Alias: A330055O14Rik; C330016G14; FLJ14581; Imp7; importin 7; Importin-7; IPO7; MGC138673; RAN binding protein 7; Ran-binding protein 7; RANBP7
• Gene Symbols: Ipo7
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human RanBP7/Importin 7.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10527
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG