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Invitrogen™ RANGAP1 Recombinant Rabbit Monoclonal Antibody (1E7R7)
Rabbit Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA535713
Description
Immunogen sequence: MASEDIAKLA ETLAKTQVAG GQLSFKGKSL KLNTAEDAKD VIKEIEDFDS LEALRLEGNT VGVEAARVIA KALEKKSELK RCHWSDMFTG RLRTEIPPAL.
Ran is a small signaling GTPase that is involved in nucleocytoplasmic transport. Two additional functions of animal Ran in the formation of spindle asters and the reassembly of the nuclear envelope in mitotic cells have been recently reported. In contrast to Ras or Rho, Ran is not associated with membranes. Instead, the spatial sequestering of its accessory proteins, the Ran GTPase-activating protein RanGAP and the nucleotide exchange factor RCC1, appears to define the local concentration of RanGTP vs. RanGDP involved in signaling. Mammalian RanGAP is bound to the nuclear pore by a mechanism involving the attachment of small ubiquitin-related modifier protein (SUMO) to its C terminus and the subsequent binding of the SUMOylated domain to the nucleoporin Nup358.
Specifications
RANGAP1 | |
Recombinant Monoclonal | |
0.13 mg/mL | |
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P46060, P46061 | |
RANGAP1 | |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RanGAP1 (P46060). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
1E7R7 | |
Unconjugated | |
RANGAP1 | |
C79654; fug1; KIAA1835; MGC20266; mKIAA1835; RAN GTPase activating protein 1; RAN GTPase activating protein 1 a; Ran GTPase activating protein 1 b; Ran GTPase activating protein 1 L homeolog; Ran GTPase activating protein 1 S homeolog; ran GTPase-activating protein 1; RANGAP; RanGAP1; rangap1.L; rangap1.S; rangap1a; rangap1-a; rangap1b; rangap1-b; rna1p; SD; segregation distorter homolog; segregation distortion; XELAEV_18023679mg; XELAEV_18025680mg | |
Rabbit | |
Affinity Chromatography | |
RUO | |
19387, 362965, 5905 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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