Invitrogen™ RANK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588904

Catalog No. PIPA588904

Description

Immunogen sequence: RGPLPQCAYG MGLPPEEEAS RTEARDQPED GADGRLPSSA RAGAGSGSSP GGQSPASGNV TGNSNSTFIS SGQVMNFKGD IIVVYVSQTS QEGAAAAAEP MGRPVQEETL ARRDSFAGNG PRFPDPCGGP EGLREPEKAS RPVQEQGGAK A; Positive Samples: HT-29, Mouse brain, Rat kidney; Cellular Location: Cell membrane, Single-pass type I membrane protein.

RANK is a member of the tumor necrosis factor receptor (TNFR) family. The full length mouse RANK cDNA encodes a type I transmembrane protein with an extracellular and a cytoplasmic domain. The extracellular domain contains two potential N-linked glycosylation sites. RANK shares significant amino acid homology with other members of the TNFR family in its extracellular four cysteine-rich repeats. Human and murine RANK share 81% amino acid identity in their extracellular domains.

Specifications

• Antigen: RANK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TNFRSF11A
• Gene Alias: CD265; FEO; LOH18CR1; loss of heterozygosity, 18, chromosomal region 1; Ly109; mRANK; ODFR; OFE; OPTB7; Osteoclast differentiation factor receptor; OSTS; Paget disease of bone 2; PDB2; Rank; receptor activator of NF-kappaB; receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; RGD1563614; TNF receptor superfamily member 11a; Tnfrsf11a; TRANCER; TRANCE-R; tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, NFKB activator
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21934, 498206, 8792
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.15 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O35305, Q9Y6Q6
• Gene Symbols: TNFRSF11A
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 466-616 of human TNFRSF11A (NP_0038301).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG