Invitrogen™ RAP1A Monoclonal Antibody (1D4-1A3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA1147

Catalog No. PIMA1147

Description

Western blot analysis of MA1-147 detects an ~21kDa protein. In IHC (paraffin) applications, this antibody has only shown reactivity with human samples.

The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.

Specifications

• Antigen: RAP1A
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
• Gene Accession No.: P62834, P62835
• Gene Symbols: RAP1A
• Immunogen: Recombinant full-length human Rap1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 1D4-1A3
• Conjugate: Unconjugated
• Gene: RAP1A
• Gene Alias: AI848598; C21KG; G-22K; GTP-binding protein; GTP-binding protein smg p21A; GTP-binding protein SMG-P21A; KREV1; Krev-1; rap 1A; RAP1; RAP1A; RAP-1A; RAP1A, member of RAS oncogene family; RAS-related protein 1a; ras-related protein Krev-1; Ras-related protein Rap-1A; RAS-related protein-1a; SMGP21
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 109905, 5906
• Content And Storage: -20°C
• Form: Liquid