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Invitrogen™ RAP1A Polyclonal Antibody
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Catalog No. PIPA587540
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Catalog No. PIPA587540 Supplier Invitrogen™ Supplier No. PA587540
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Rabbit Polyclonal Antibody

Positive Samples: U-87MG, HL-60, Mouse lung, Mouse kidney, Rat kidney, Rat brain; Cellular Location: Cell junction, Cell membrane, Cytoplasm, Early endosome, Lipid-anchor, perinuclear region Immunogen sequence: SYRKQVEVDC QQCMLEILDT AGTEQFTAMR DLYMKNGQGF ALVYSITAQS TFNDLQDLRE QILRVKDTED VPMILVGNKC DLEDERVVGK EQGQNLARQW.

The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAP1A
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.78 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene RAP1A
Gene Accession No. P62834
Gene Alias AI848598; C21KG; G-22K; GTP-binding protein; GTP-binding protein smg p21A; GTP-binding protein SMG-P21A; KREV1; Krev-1; rap 1A; RAP1; RAP1A; RAP-1A; RAP1A, member of RAS oncogene family; RAS-related protein 1a; ras-related protein Krev-1; Ras-related protein Rap-1A; RAS-related protein-1a; SMGP21
Gene Symbols RAP1A
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 39-138 of human Rap1A (NP_0028751).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5906
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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