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Invitrogen™ RAP1A Polyclonal Antibody
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Catalog No. PA129451
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50 μg
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PA129451 50 μg
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Catalog No. PA129451 Supplier Invitrogen™ Supplier No. PA129451
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Description

Rabbit Polyclonal Antibody

It is expected to cross-react with zebrafish and C. elegans based on sequence homology of 100% and 94%, respectively. PA1-29451 has been successfully used in Western blot applications where a band of 25 kDa is detected. Positive control: rat brain tissue extract.

The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAP1A
Applications Western Blot
Classification Polyclonal
Concentration 0.95 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene RAP1A
Gene Accession No. P62834, P62835, P62836
Gene Alias AI848598; C21KG; G-22K; GTP-binding protein; GTP-binding protein smg p21A; GTP-binding protein SMG-P21A; KREV1; Krev-1; rap 1A; RAP1; RAP1A; RAP-1A; RAP1A, member of RAS oncogene family; RAS-related protein 1a; ras-related protein Krev-1; Ras-related protein Rap-1A; RAS-related protein-1a; SMGP21
Gene Symbols RAP1A
Host Species Rabbit
Immunogen Synthetic peptide corresponding to a portion of human Rap1a. Peptide differs from Rap1b by two residues.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100351588, 109905, 295347, 5906
Target Species Human, Mouse, Rat, Rabbit
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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