Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

RAP80 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

$151.31

Specifications

Antigen RAP80
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Form Liquid
View More Specs

Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-155-8388
Encompass_Preferred
View Documents
Bethyl Laboratories, Inc
A300764AT
20 μL
Each of 1 for $151.31
Only null left
Add to Cart
 
Description

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

RAP80 was initially identified as zinc-finger containing nuclear protein that is highly expressed in testis and interacts with the retinoid-related testis-associated receptor (RTR). Later experiments revealed that RAP80 is recruited by the Coiled-coil domain 98 (CCDC98) protein to the breast cancer-1 protein BRCA1, allowing the formation of BRCA1 foci in response to DNA damage caused by ionizing radiation. Both RAP80 and CCDC98 are required for DNA damage resistance, G2-M checkpoint control, and DNA repair. Cells depleted of either RAP80 or CCDC98 exhibited increased sensitivity to ionizing radiation, although not as much as in BRCA1-depleted cells, suggesting that RAP80 and CCDC98 control only part of the DNA damage response role of BRCA1. At least four isoforms of RAP80 are known to exist.
Specifications

Specifications

RAP80
Polyclonal
Liquid
RUO
TBS with 0.1% BSA and 0.09% sodium azide
RAP80, X2HRIP110; BRCA1-A complex subunit RAP80; receptor associated protein 80; receptor-associated protein 80; retinoid X receptor-interacting protein 110; retinoid x receptor interacting protein; ubiquitin interaction motif-containing protein 1
UIMC1
IgG
Antigen affinity chromatography
Antibody
Immunohistochemistry, Western Blot
Unconjugated
Rabbit
Human
Q96RL1
51720
Between 650 and C-term
Primary
4° C
UIMC1
Videos
SDS
Documents

Documents

Product Certifications
Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.