Invitrogen™ RAPGEF1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116652

Catalog No. PIPA5116652

Description

Positive Samples: Mouse liver Immunogen sequence: ARGVAARPGT LHDFHSHEIA EQLTLLDAEL FYKIEIPEVL LWAKEQNEEK SPNLTQFTEH FNNMSYWVRS IIMLQEKAQD RERLLLKFIK IMKHLRKLNN FNSYLAILSA LDSAPIRRLE WQKQTSEGLA EYCTLIDSSS SFRAYRAALS EVEPPCIPYL GLILQDLTFV HLGNPDYIDG KVNFSKRWQQ FNILDSMRCF QQAHYDMRRN DDIINFFNDF SDHLAEEALW ELSLKIKPRN ITRRKTDREE KT.

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.

Specifications

• Antigen: RAPGEF1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAPGEF1
• Gene Alias: 4932418O06Rik; C3G; C3G-1; C3G-2; CRK SH3-binding GNRP; GRF2; guanine nucleotide releasing factor 2; Guanine nucleotide-releasing factor 2; guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene); Protein C3G; Rap guanine nucleotide exchange factor (GEF) 1; Rap guanine nucleotide exchange factor 1; Rapgef1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 107746, 2889, 63881
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.93 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q13905
• Gene Symbols: RAPGEF1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 844-1095 of human RAPGEF1 (NP_9413721).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG