Invitrogen™ RAPGEF4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA556019

Catalog No. PIPA556019

Description

Immunogen sequence: VIYGKGVVCT LHEGDDFGKL ALVNDAPRAA SIVLREDNCH FLRVDKEDFN RILRDVEANT VRLKEHDQDV LVLEKVPAGN RASNQGNSQP QQKYTVMSGT PEKILEHFLE TIRLEATLNE ATDSVLNDFI MMHCVFMPNT QLC Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 98%.

Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2.

Specifications

• Antigen: RAPGEF4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rapgef4
• Gene Alias: 1300003D15Rik; 5730402K07Rik; 6330581N18Rik; cAMP-dependent Rap1 guanine-nucleotide exchange factor; cAMP-GEFII; cAMP-regulated guanine nucleotide exchange factor II; cAMP-regulated guanine nucleotide exchange factor IIB; CAMPS; Cgef2; EPAC; epac 2; Epac2; Epac-2; Exchange factor directly activated by cAMP 2; exchange protein directly activated by cAMP 2; gefii; mKIAA4040; Nbla00496; putative protein product of Nbla00496; Rap guanine nucleotide exchange factor (GEF) 4; Rap guanine nucleotide exchange factor 4; RAP guanine-nucleotide-exchange factor (GEF) 4; Rapgef4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11069
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8WZA2
• Gene Symbols: Rapgef4
• Immunogen: Recombinant protein corresponding to Human RAPGEF4. Recombinant protein control fragment (Product #RP-95156).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG