Invitrogen™ RAPSN Monoclonal Antibody (1234)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA1746

Catalog No. MA1746

Description

MA1-746 detects rapysn from mouse, rat, chicken, amphibian and fish samples. MA1-746 has been used in immunochemistry procedures using cryosections, immunocytochemistry, immunofluorescence and Western Blot procedures. By Western blot, this antibody detects a 48 kDa protein representing rapsyn from Torpedo californica electrocyte cell extracts. The MA1-746 immunogen is whole purified rapsyn from Torpedo californica electric organ postsynaptic membrane.

This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specifications

• Antigen: RAPSN
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1 mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: O42393, P12672
• Gene Symbols: RAPSN
• Immunogen: Whole purified rapsyn from Torpedo californica electric organ postsynaptic membrane.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse, Rat, Chicken, Amphibian, Fish
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot, Immunocytochemistry
• Clone: 1234
• Conjugate: Unconjugated
• Gene: RAPSN
• Gene Alias: 43 kD receptor-associated protein of the synapse; 43 kda postsynaptic protein; 43 kDa receptor-associated protein of the synapse; 43kDa; 43kDa acetylcholine receptor-associated protein; acetylcholine receptor-associated 43 kda protein; AChR associated protein at synapses; acetylcholine receptor associated protein at synapses; 43kDa protein; likely to cluster nicotinic AChRs; CMS11; CMS1D; CMS1E; CMS4C; FADS; MGC3597; Nraps; Raps; Rapsn; rapsyn; receptor associated protein of the synapse; receptor-associated protein of the synapse; receptor-associated protein of the synapse, 43 kDa; receptor-associated protein of the synapse, 43kD; RING finger protein 205; RNF205; twitch once; two
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 19400, 362161, 395986
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid