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Invitrogen™ RAR gamma-1,2 Polyclonal Antibody
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Catalog No. PIPA5121101
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100 μL
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PIPA5121101 100 μL
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Catalog No. PIPA5121101 Supplier Invitrogen™ Supplier No. PA5121101
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Description

Rabbit Polyclonal Antibody

Positive test controls include: Mouse lung, Rat kidney. The target is usually found in the following locations: Nucleus. Immunogen sequence: KKEVKEEGSP DSYELSPQLE ELITKVSKAH QE.

Retinoic acid, a metabolite of vitamin A, is necessary for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. Retinoic acid functions through its interaction with the nuclear protein, retinoic acid receptor (RAR). RAR belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. RAR exists as three major subtypes: alpha, beta and gamma. Two main isoforms of RAR gamma exist: RAR gamma-1 has been found to be predominantly expressed in skin, while RAR gamma-2 has been found early in embryogenesis and in embryonal carcinoma cells. RAR gamma is also known as RARD. The corresponding gene for the retinoic acid receptor gamma 1 is NR1B3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAR gamma-1,2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.82 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RARG
Gene Accession No. P13631, P18911
Gene Symbols RARG
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 168-199 of human RARG (NP_0009571).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19411, 5916, 685072
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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