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Invitrogen™ RAR gamma-1 Polyclonal Antibody
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Catalog No. PIPA5113593
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PIPA5113593 100 μL
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Catalog No. PIPA5113593 Supplier Invitrogen™ Supplier No. PA5113593
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YPGAGFPFAF PGALRGSPPF EMLSPSFRGL GQPDLPKEMA SLSVETQSTS For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Sheep: 100%.

Retinoic acid, a metabolite of vitamin A, is necessary for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. Retinoic acid functions through its interaction with the nuclear protein, retinoic acid receptor (RAR). RAR belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. RAR exists as three major subtypes: alpha, beta and gamma. Two main isoforms of RAR gamma exist: RAR gamma-1 has been found to be predominantly expressed in skin, while RAR gamma-2 has been found early in embryogenesis and in embryonal carcinoma cells. RAR gamma is also known as RARD. The corresponding gene for the retinoic acid receptor gamma 1 is NR1B3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAR gamma-1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene Rarg
Gene Accession No. P13631, P18911
Gene Alias Nr1b3; Nuclear receptor subfamily 1 group B member 3; RAR gamma 2; RAR Gamma-1; RARC; RARD; Rarg; RAR-gamma; RARgamma2; retinoic acid; retinoic acid nuclear receptor gamma variant 1; retinoic acid nuclear receptor gamma variant 2; retinoic acid receptor; retinoic acid receptor gamma; retinoic acid receptor gamma 4; retinoic acid receptor, gamma
Gene Symbols Rarg
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N terminal region of human RARG (aa 20-69).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19411, 5916
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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