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  6. RAR-gamma Monoclonal Antibody (4 gamma-7A11), Active Motif™ 

RAR-gamma Monoclonal Antibody (4 gamma-7A11), Active Motif™
SDP

Catalog No. 501993011
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50-199-3011 100 μg
50-199-3012 10 μg
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Catalog No. 50-199-3011 Supplier Active Motif Supplier No. 39973
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Description

Mouse Monoclonal Antibody

Retinoic acid, a metabolite of vitamin A, is necessary for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. Retinoic acid functions through its interaction with the nuclear protein, retinoic acid receptor (RAR). RAR belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. RAR exists as three major subtypes: alpha, beta and gamma. Two main isoforms of RAR gamma exist: RAR gamma-1 has been found to be predominantly expressed in skin, while RAR gamma-2 has been found early in embryogenesis and in embryonal carcinoma cells. RAR gamma is also known as RARD. The corresponding gene for the retinoic acid receptor gamma 1 is NR1B3.

Specifications

Antigen RAR-gamma
Applications Gel Shift, Immunohistochemistry, Western Blot
Classification Monoclonal
Clone 4 gamma-7A11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Rarg
Gene Accession No. P13631
Gene Alias NR1B3; Nuclear receptor subfamily 1 group B member 3; RAR gamma 2; RAR Gamma-1; RARC; RARD; Rarg; RAR-gamma; RARgamma2; retinoic acid nuclear receptor gamma variant 1; retinoic acid nuclear receptor gamma variant 2; Retinoic acid receptor gamma; retinoic acid receptor gamma 4; retinoic acid receptor, gamma
Gene Symbols Rarg
Host Species Mouse
Immunogen This RAR-gamma antibody was raised against a recombinant protein corresponding to amino acids 428-441 (F-region) of human RAR gamma.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5916
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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