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Invitrogen™ RARS Monoclonal Antibody (C9), Invitrogen™

Catalog No. PIMA543616
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100 μL
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PIMA543616 20 μL
PIMA543615 100 μL
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Catalog No. PIMA543616 Supplier Invitrogen™ Supplier No. MA543616
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Description

Mouse Monoclonal Antibody

The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. ArgRS (Arginyl-tRNA synthetase), also known as RARS or DALRD1, belongs to the class-I aminoacyl-tRNA synthetase family that includes the related proteins, LeuRS, ValRS and IleRS. These proteins are large monomeric proteins and play a major role in catalyzing the aminoacylation of tRNA by their cognate amino acid. ArgRS localizes to the cytoplasm and exists as a monomer but can also associate with other tRNA synthetases and auxiliary proteins to form a multisubunit complex. In the presence of ATP, arginine (Arg) and tRNA, ArgRS joins Arg to tRNA(Arg) at its synthetic active site. Two cytoplasmic forms of ArgRS have been described in mammals, differing by the addition of a 73 amino acid sequence that is required for ArgRS assembly into the multisubunit complex.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RARS
Applications Western Blot
Classification Monoclonal
Clone C9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene RARS1
Gene Accession No. P54136
Gene Alias 2610011N19Rik; 2610037E21Rik; AL033339; arginine tRNA ligase 1, cytoplasmic; arginine--tRNA ligase, cytoplasmic; Arginyl-tRNA synthetase; arginyl-tRNA synthetase, cytoplasmic; argRS; AW985894; DALRD1; HLD9; MGC8641; RARS
Gene Symbols RARS1
Host Species Mouse
Immunogen Met1-Pro146 (Accession P54136), with N-terminal His Tag.
Purification Method Protein A/G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5917
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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