Invitrogen™ RARS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552035

Catalog No. PIPA552035

Description

Immunogen sequence: TIIGESISRL FEFAGYDVLR LNHVGDWGTQ FGMLIAHLQD KFPDYLTVSP PIGDLQVFYK ESKKRFDTEE EFKKRAYQCV VLLQGKNPDI TKAWKLICDV SRQELNKIYD ALDVSLIERG ESFYQDRMND IVKEFEDRGF VQVDDGRKIV Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.

The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. ArgRS (Arginyl-tRNA synthetase), also known as RARS or DALRD1, belongs to the class-I aminoacyl-tRNA synthetase family that includes the related proteins, LeuRS, ValRS and IleRS. These proteins are large monomeric proteins and play a major role in catalyzing the aminoacylation of tRNA by their cognate amino acid. ArgRS localizes to the cytoplasm and exists as a monomer but can also associate with other tRNA synthetases and auxiliary proteins to form a multisubunit complex. In the presence of ATP, arginine (Arg) and tRNA, ArgRS joins Arg to tRNA(Arg) at its synthetic active site. Two cytoplasmic forms of ArgRS have been described in mammals, differing by the addition of a 73 amino acid sequence that is required for ArgRS assembly into the multisubunit complex.

Specifications

• Antigen: RARS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RARS1
• Gene Alias: 2610011N19Rik; 2610037E21Rik; AL033339; arginine tRNA ligase 1, cytoplasmic; arginine--tRNA ligase, cytoplasmic; Arginyl-tRNA synthetase; arginyl-tRNA synthetase, cytoplasmic; argRS; AW985894; DALRD1; HLD9; MGC8641; RARS
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5917
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P54136
• Gene Symbols: RARS1
• Immunogen: Recombinant protein corresponding to Human RARS. Recombinant protein control fragment (Product #RP-102263).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov