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Invitrogen™ Ras (G12V Mutant) Polyclonal Antibody
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Catalog No. PIPA578087
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100 μL
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PIPA578087 100 μL
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Catalog No. PIPA578087 Supplier Invitrogen™ Supplier No. PA578087
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Description

Rabbit Polyclonal Antibody

Positive Control: NRAS(G12V)-transfected 293T Predicted Reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Dog (100%), Pig (100%), Chicken (100%), Bovine (100%), Guinea pig (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Ras is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. The process of shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in Ras gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ras (G12V Mutant)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene NRAS
Gene Accession No. P01111
Gene Alias ALPS4; CMNS; GTPase NRas; HRAS1; NCMS; neuroblastoma RAS viral (v-ras) oncogene homolog; neuroblastoma RAS viral oncogene homolog; NRAS; N-ras; N-ras protein part 4; NRAS1; NS6; Transforming protein N-Ras; v-ras neuroblastoma RAS viral oncogene homolog
Gene Symbols NRAS
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide surrounding mutant G12V of human K-Ras. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4893
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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