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RASA1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982766
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50-198-2766 100 μL
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Catalog No. 50-198-2766 Supplier Bioss Supplier No. BS13280R
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Description

Rabbit Polyclonal Antibody

TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.

Specifications

Antigen RASA1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene RASA1
Gene Accession No. P20936
Gene Alias BOS_8464; CMAVM; CM-AVM; GAP; GAPX; GTPase-activating protein; p120; p120 RAS GTPase activating protein; p120GAP; p120RASGAP; p120-rasGAP; PKWS; Ras GTPase-activating protein 1; Ras p21 protein activator; RAS p21 protein activator (GTPase activating protein RAS p21); RAS p21 protein activator (GTPase activating protein) 1; RAS p21 protein activator 1; RASA; Rasa1; RASGAP; triphosphatase-activating protein
Gene Symbols RASA1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Ras GTPase-activating protein 1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5921
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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