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Invitrogen™ RASA3 Polyclonal Antibody
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Catalog No. PIPA530445
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100 μL
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PIPA530445 100 μL
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Catalog No. PIPA530445 Supplier Invitrogen™ Supplier No. PA530445
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: SK-N-SH, IMR32, SK-N-AS, mouse brain. Predicted reactivity: Mouse (93%), Rat (92%), Xenopus laevis (86%), Chicken (89%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Human GAP1-InsP4 BP, also designated Ras p21 protein activator (GTPase-activating protein) 3 [Ins(1,3,4,5)P4-binding protein], is an 829-amino acid protein that binds phospholipids in both a calcium-dependent and -independent manner. GAP1, one of the Ras GTPase-activating protein families, comprises four distinct genes, including GAP1(m), GAP1-InsP4 BP, MRASAL (murine Ras GTPase-activating-like) and KIAA0538. This family contains an N-terminal tandem C2 domain, a GAP-related domain and a C-terminal pleckstrin homology (PH) domain. The PH domains of GAP1-InsP4 BP are essential for membrane targeting via binding of specific phospholipids. Following agonist-stimulated PtdIns(3,4,5)P(3) production, group I family PH domain containing proteins like GAP1-InsP4 BP specifically bind inositol phosphates, which are subsequently targeted to the plasma membrane.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RASA3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene RASA3
Gene Accession No. Q14644, Q60790
Gene Alias AI326412; C86362; E130011G04; GAP1(IP4BP); GAP1-InsP4 BP; GAP1IP4BP; GAPIII; GAPIII activator 3; GTPase activating protein III; GTPase-activating protein 1 family, inositol 1,3,4,5-tetrakisphosphate-binding protein; ins P4-binding protein; Ins(1,3,4,5)P4-binding protein; ras GTPase-activating protein 3; Ras GTPase-activating protein III; RAS p21 protein activator 3; Rasa3; RP11-245B11.3; R-Ras gap; R-Ras GTP activating protein; R-ras GTPase activating protein; R-ras RTPase activating protein-3; scat
Gene Symbols RASA3
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human RASA3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19414, 22821
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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