RASA3 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-6931	100 μL

Catalog No. 50-198-6931 Supplier Bioss Supplier No. BS5954R

Description

Rabbit Polyclonal Antibody

Human GAP1-InsP4 BP, also designated Ras p21 protein activator (GTPase-activating protein) 3 [Ins(1,3,4,5)P4-binding protein], is an 829-amino acid protein that binds phospholipids in both a calcium-dependent and -independent manner. GAP1, one of the Ras GTPase-activating protein families, comprises four distinct genes, including GAP1(m), GAP1-InsP4 BP, MRASAL (murine Ras GTPase-activating-like) and KIAA0538. This family contains an N-terminal tandem C2 domain, a GAP-related domain and a C-terminal pleckstrin homology (PH) domain. The PH domains of GAP1-InsP4 BP are essential for membrane targeting via binding of specific phospholipids. Following agonist-stimulated PtdIns(3,4,5)P(3) production, group I family PH domain containing proteins like GAP1-InsP4 BP specifically bind inositol phosphates, which are subsequently targeted to the plasma membrane.

Specifications

• Antigen: RASA3
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: RASA3
• Gene Accession No.: Q14644
• Gene Alias: AI326412; C86362; E130011G04; GAP1(IP4BP); GAP1-InsP4 BP; GAP1IP4BP; GapIII; GAPIII activator 3; GTPase activating protein III; GTPase-activating protein 1 family, inositol 1,3,4,5-tetrakisphosphate-binding protein; Ins P4-binding protein; Ins(1,3,4,5)P4-binding protein; Ras GTPase-activating protein 3; Ras GTPase-activating protein III; RAS p21 protein activator 3; RASA3; RP11-245B11.3; R-ras GAP; R-Ras GTP activating protein; R-ras GTPase activating protein; R-ras RTPase activating protein-3; scat
• Gene Symbols: RASA3
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human RASA3.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 22821
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG