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Invitrogen™ RASA4 Polyclonal Antibody
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Catalog No. PIPA560197
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100 μL
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PIPA560197 100 μL
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Catalog No. PIPA560197 Supplier Invitrogen™ Supplier No. PA560197
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MSSSFKKLYF SLTTEALSFA KTPSSKKSAL IKLANIRAAE KVEEKSFGGS HVMQVIYTDD AGRPQTAYLQ CKC Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 86%.

This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RASA4
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RASA4
Gene Accession No. O43374
Gene Alias AA793972; AW112107; BB079060; Ca2+promoted Ras inactivator; Ca2+-promoted Ras inactivator; calcium-promoted RAS inactivator; Capri; GAPL; Kiaa0538; Ras GTPase-activating protein 4; RAS p21 protein activator 4; RASA4; RasGAP-activating-like protein 2; RGD1565457
Gene Symbols RASA4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RASA4. Recombinant protein control fragment (Product #RP-99250).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10156
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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